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Teaching File
Breast Cases
Resources
Articles
Lectures
About
My Background
Scholarly Works
Teaching
Professional Activites
Unknown Case 2
49 y/o F with presents with a left breast palpable area. What is the most likely diagnosis?
Click for Answer
INVASIVE LOBULAR CARCINOMA
5-10% of breast cancers
Distinct from invasive
ductal
carcinoma
More often
multicentric and bilateral
(10-15%)
Loss of
E-cadherin
(biomarker) **
Cells of ILC often preserve the architecture of the ducts, which limits the sensitivity of detection using mammography
Mammo: “
Shrinking breast
” or reduced compressibility
US: ill-defined hypoechoic mass
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