Unknown Case 5

42 y/o F with presents with left nipple discharge. What is the most likely diagnosis?


  • Symptomatic bloody or clear nipple discharge: especially if unilateral, spontaneous, persistent
  • Central – within a major subareolar duct and often solitary
  • Peripheral – within a TDLU and may be multiple; higher likelihood of malignancy
  • Mammo: dilated duct(s) or circumscribed mass
  • Filling defect on galactogram
  • US: intraductal mass with vascular stalk; dilated fluid-filled duct
  • Tx (controversial): Surgical excision, especially if associated with atypia